Intelliscore ExoDx and PCA-3


For patients that do have an elevated PSA, there are other screening tools that fit in nicely before doing a biopsy.  A few of those are different tests – one of them is a blood test called a OPKO 4Kscore and the second one is a urine test called Intelliscore ExoDx Prostate.  These are basically other biomarker tests to help us figure out if a patient may have cancer and a more significant type of cancer that would warrant treatment.

The PCA-3 is another urine  biomarker test that is followed by a digital rectal examination (DRE) – so this does require an invasive prostate exam prior to the urine testing.

My thoughts are with the new ExoDx Prostate, that PCA-3 will fall off in favor, because PCA-3 is not shown as accurate testing compared to ExoDx Prostate, but it is certainly still useful and can be used in addition to typical PSA testing and fits nicely into consideration before patients decide to do prostate imaging or a prostate biopsy.  PCA-3 is useful, but I would prefer Intelliscore ExoDx Prostate because the testing sensitivity is also better.

4 thoughts on “Intelliscore ExoDx and PCA-3

  1. John Tucker Reply

    Hi Doc, My PSA is 0.6 and the EXODX blood test result was ‘minimally elevated’ and the nurse practioner who digitally examined my prostate said it felt asymmetric (although the technician who did a separate sonor scan said after examining it before and after urinating that nothing abnormal was detected). The Nurse practioner wants now to order a biopsy of my prostate. Is this the correct path ?

  2. Patti Reply

    Hello Doctor, my husband had a PSA test done and this level was 9. He then had the Intelliscore urine test done and this score was 20.8. This seems extremely high and I’m very nervous. He’s scheduled for an MRI. Is there a chance that the Intelliscore can give an inaccurate score?

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